Nancy Stambler Selected Research

methylnaltrexone

1/2022	First-Dose Efficacy of Methylnaltrexone in Patients with Severe Medical Illness and Opioid-Induced Constipation: A Pooled Analysis.
9/2021	The influence of brain metastases on the central nervous system effects of methylnaltrexone: a post hoc analysis of 3 randomized, double-blind studies.
6/2021	Correction to: The Influence of Age on Central Effects of Methylnaltrexone in Patients with Opioid-Induced Constipation.
1/2021	Subcutaneous Methylnaltrexone for Treatment of Opioid-Induced Constipation in Cancer versus Noncancer Patients: An Analysis of Efficacy and Safety Variables from Two Studies.
1/2021	Attrition of methylnaltrexone treatment-emergent adverse events in patients with chronic noncancer pain and opioid-induced constipation: a post hoc pooled analysis of two clinical trials.
1/2021	The Influence of Age on Central Effects of Methylnaltrexone in Patients with Opioid-Induced Constipation.
3/2020	Subcutaneous methylnaltrexone for opioid-induced constipation in advanced-illness patients with or without active cancer.
1/2019	Safety of oral methylnaltrexone for opioid-induced constipation in patients with chronic noncancer pain.
1/2017	Randomized, Double-Blind Trial of Oral Methylnaltrexone for the Treatment of Opioid-Induced Constipation in Patients with Chronic Noncancer Pain.
2/2012	Subcutaneous methylnaltrexone for treatment of acute opioid-induced constipation: phase 2 study in rehabilitation after orthopedic surgery.

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Nancy Stambler Research Topics

Disease

14	Opioid-Induced Constipation 01/2022 - 05/2008
11	Pain (Aches) 01/2022 - 05/2008
7	Neoplasms (Cancer) 01/2022 - 01/2018
5	Substance Withdrawal Syndrome (Withdrawal Symptoms) 09/2021 - 05/2008
5	Prostatic Neoplasms (Prostate Cancer) 01/2021 - 01/2017
3	Constipation 01/2021 - 05/2008
3	Nausea 01/2021 - 05/2011
2	Vomiting 01/2021 - 05/2011
2	Circulating Neoplastic Cells 01/2020 - 01/2019
2	Paraganglioma (Paragangliomas) 01/2019 - 01/2018
2	Pheochromocytoma 01/2019 - 01/2018
2	Body Weight (Weight, Body) 10/2010 - 05/2008
1	Brain Neoplasms (Brain Tumor) 09/2021
1	Stroke (Strokes) 01/2021
1	Dementia (Dementias) 01/2021
1	Neutropenia 01/2020
1	Anemia 01/2020
1	Fatigue 01/2020
1	Cardiotoxicity 01/2019
1	Diarrhea 01/2019
1	Abdominal Pain (Pain, Abdominal) 01/2019
1	Ileus 05/2011
1	Weight Loss (Weight Reduction) 04/2003
1	Obesity 04/2003
1	Injection Site Reaction 04/2003

Drug/Important Bio-Agent (IBA)

15	methylnaltrexone FDA Link 01/2022 - 05/2008
13	Opioid Analgesics (Opioids)IBA 01/2022 - 05/2008
6	Narcotic Antagonists (Opioid Antagonists)IBA 09/2021 - 05/2008
4	LaxativesIBA 01/2022 - 05/2008
4	AntigensIBA 01/2021 - 01/2017
3	Morphine (MS Contin)FDA LinkGeneric 01/2021 - 01/2017
2	Opioid Receptors (Opioid Receptor)IBA 01/2021 - 05/2008
2	PSMA ADCIBA 01/2020 - 01/2019
2	Prostate-Specific Antigen (Semenogelase)IBA 01/2020 - 01/2019
1	Analgesics (Analgesic Drugs)IBA 01/2021
1	2- (3- (1- carboxy- 5- ((6- fluoropyridine- 3- carbonyl)amino)pentyl)ureido)pentanedioic acidIBA 01/2021
1	abirateroneIBA 01/2020
1	Biomarkers (Surrogate Marker)IBA 01/2020
1	ElectrolytesIBA 01/2020
1	enzalutamideIBA 01/2020
1	Docetaxel (Taxotere)FDA Link 01/2019
1	Antihypertensive Agents (Antihypertensives)IBA 01/2019
1	Tumor Biomarkers (Tumor Markers)IBA 01/2019
1	Immunoconjugates (Immunoconjugate)IBA 01/2019
1	3-Iodobenzylguanidine (Iobenguane)IBA 01/2018
1	Pharmaceutical PreparationsIBA 01/2018
1	leronlimabIBA 10/2010
1	Antiviral Agents (Antivirals)IBA 10/2010
1	mu Opioid Receptors (mu Opioid Receptor)IBA 01/2009
1	LeptinIBA 04/2003
1	Ciliary Neurotrophic Factor (CNTF)IBA 04/2003

Therapy/Procedure

7	Analgesia 01/2022 - 05/2008
4	Therapeutics 01/2020 - 05/2008
2	Prostatectomy (Retropubic Prostatectomy) 01/2021 - 01/2017
2	Castration 01/2020 - 01/2019
2	Intravenous Infusions 01/2019 - 10/2010
1	Pain Management 01/2021
1	Lymph Node Excision (Lymph Node Dissection) 01/2021
1	Drug Therapy (Chemotherapy) 01/2019
1	Orthopedic Procedures 02/2012
1	Colectomy 05/2011
1	Investigational Therapies (Experimental Therapy) 05/2008